• Ventolin



    Ventolin tablets (pills) and Ventolin Inhaler - these are prescription medicines used for the treatment of bronchial tubes and lungs, in patients with bronchial asthma. These drugs are stimulants of the beta-adrenergic receptors.


    Available forms of release:

    Ventolin Inhaler — aerosol for inhalation, produced by GlaxoSmithKline (gsk) contains 100 mcg of Salbutamol Sulfate, 200 doses per inhaler. It is chlorofluorocarbon free.


    Ventolin pill - a bronchodilator, each containing 2 / 4 mg of Salbutamol Sulfate. The most popular generic is made by Cipla, it is Asthalin-4. Salbutamol Sulfate tablets are also known as Accuneb / Airet / ProAir / Proventil / Volmax / VoSpire.


    That’s how it works

    Generic Ventolin suppresses the release of the following bio-active materials from the mast cells: leukotriene, histamine, prostaglandin and others. Inhibits bronchial reactivity (early and late), increases lung capacity, lowers the resistance in the airways, activates the function of ciliated epithelium, increases the mucociliary clearance, enhances slime secretion, has a distinct bronchodilatory effect. It prevents bronchospasm induced by allergens. Both forms of generic ventolin are applicable for the prevention or relief of bronchospasm. Salbutamol Sulfate affects the secretion of insulin and glycogenolysis, has a hyperglycemic and lipolytic effect.


    It has a positive chronotropic and inotropic effect.


    Indications:

  • 1) Bronchial asthma: prevention and relief of bronchospasm, as a component in the complex treatment of bronchial asthma (including status asthmaticus).
  • 2) With the preventive purpose, the drugs are used immediately prior to contact with the allergen, or before physical activity.
  • 3) Also these medications are used in patients with chronic obstructive lung disease, which is accompanied by an invertible bronchial obstruction.

  • Side effects:

  • - angioneurotic edema, bronchospasm, urticaria, hypotension up to collapse;
  • - reduction in the level of potassium in the blood plasma;
  • - headache, tremor, irritability and hyperactivity;
  • - tachycardia, heart rhythm disturbances, abnormal rhythm of heartbeats, atrial fibrillation;
  • - dilation of blood vessels as a result of relaxation of the muscular walls of blood vessels;
  • - paradoxical bronchospasm;
  • - irritation of the mucous membrane of the oral cavity and pharynx;
  • - muscle cramps.

  • Contraindications:

  • 1) Hypersensitivity to any component of the drug.
  • 2) Children age up to six years.
  • 3) Chronic heart failure, hypertension, hyperthyroidism, tachyarrhythmia, pheochromocytoma.
  • 4) Pregnancy (drug is given only if the benefit to the mother outweighs any potential risk to the fetus).
  • 5) Lactation.

  • In case of bronchial asthma, Ventolin must not be the only or primary component of treatment. Increasing needs for the use of β2-agonists of a short action to control asthma symptoms become an evidence of disease progression. This state is dangerous for the patient, so the treatment plan should be revised. Overdose by the drug can lead to adverse consequences, that's why the issue of dosage correction must be solved only by your doctor.


    Do not take this drug along with:

  • 1) non-selective beta-blockers (propranolol);
  • 2) CNS stimulants;
  • 3) cardiac glycosides;
  • 4) theophylline and other xanthines;
  • 5) remedies for inhalation anesthesia;
  • 6) anticholinergics;
  • 7) steroids and diuretics.


  • Overdose:

    In case of overdose following symptoms appear: decrease in blood pressure, painful fast heart beat, rapid heart rate, vomiting, muscle tremors, anxiety, delirium. Rarely - seizures, delusion. In the blood - lack of potassium, inadequate clearance of lactic acid from the blood, low level of phosphate, increase in the total number of WBCs. There may be a respiratory alkalosis (due to low levels of carbon dioxide). The treatment is symptomatic, the therapist prescribes medicines from the group of cardioselective beta-blockers.